SAFETY DATA SHEETS
According to Globally Harmonized System of Classification and Labelling of
Chemicals (GHS) - Sixth revised edition
Version: 1.0
Creation Date: Aug 10, 2017
Revision Date: Aug 10, 2017
1.Identification
1.1 GHS Product identifier
Product name catechol
1.2 Other means of identification
Product number-
Other names 1,2-dihydroxybenzene
1.3 Recommended use of the chemical and restrictions on use
Identified
uses
For industry use only. Catechol is used as a photographic developer, a developer for fur dyes, as an intermediate for antioxidants
in rubber and lubricating oils, in polymerization inhibitors, and in pharmaceuticals.
Uses
advised
against
no data available
1.4 Supplier's details
1.5 Emergency phone number
Emergency phone number-
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).
2.Hazard identification
2.1 Classification of the substance or mixture
Acute toxicity - Oral, Category 4
Acute toxicity - Dermal, Category 4
Skin irritation, Category 2
Eye irritation, Category 2
2.2 GHS label elements, including precautionary statements
Pictogram(s)
Signal word Warning
Hazard statement(s)
H302 Harmful if swallowed
H312 Harmful in contact with skin
H315 Causes skin irritation
H319 Causes serious eye irritation
Precautionary
statement(s)
Prevention
P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
Response
P301+P312 IF SWALLOWED: Call a POISON CENTER/doctor/…if you feel unwell.
P330 Rinse mouth.
P302+P352 IF ON SKIN: Wash with plenty of water/...
P312 Call a POISON CENTER/doctor/…if you feel unwell.
P321 Specific treatment (see ... on this label).
P362+P364 Take off contaminated clothing and wash it before reuse.
P332+P313 If skin irritation occurs: Get medical advice/attention.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and
easy to do. Continue rinsing.
P337+P313 If eye irritation persists: Get medical advice/attention.
Storage none
Disposal P501 Dispose of contents/container to ...
2.3 Other hazards which do not result in classification
none
3.Composition/information on ingredients
3.1 Substances
Chemical name Common names and synonyms CAS numberEC numberConcentration
catechol catechol 120-80-9 none 100%
4.First-aid measures
4.1 Description of necessary first-aid measures
General advice
Consult a physician. Show this safety data sheet to the doctor in attendance.
If inhaled
Fresh air, rest. Artificial respiration may be needed. Refer for medical attention.
In case of skin contact
Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention .
In case of eye contact
Rinse with plenty of water (remove contact lenses if easily possible). Refer immediately for medical attention.
If swallowed
Rinse mouth. Give one or two glasses of water to drink. Refer immediately for medical attention.
4.2 Most important symptoms/effects, acute and delayed
DUST: Irritating to eyes, nose and throat. If inhaled will cause coughing or difficult breathing. SOLID: Will burn skin and eyes. Harmful if
swallowed. (USCG, 1999)
4.3 Indication of immediate medical attention and special treatment needed, if necessary
Immediate first aid: Ensure that adequate decontamination has been carried out. If patient is not breathing, start artificial respiration, preferably with
a demand-valve resuscitator, bag-valve-mask device, or pocket mask, as trained. Perform CPR as necessary. Immediately flush contaminated
eyes with gently flowing water. Do not induce vomiting. If vomiting occurs, lean patient forward or place on left side (head-down position, if
possible) to maintain an open airway and prevent aspiration. Keep patient quiet and maintain normal body temperature. Obtain medical attention.
/Phenols and related compounds/
5.Fire-fighting measures
5.1 Extinguishing media
Suitable extinguishing media
To fight fire, use water, carbon dioxide, dry chemical
5.2 Specific hazards arising from the chemical
Combustible. POISONOUS GASES MAY BE PRODUCED WHEN HEATED. May form toxic fumes at high temperatures. (USCG, 1999)
5.3 Special protective actions for fire-fighters
Wear self-contained breathing apparatus for firefighting if necessary.
6.Accidental release measures
6.1 Personal precautions, protective equipment and emergency procedures
Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel
to safe areas. Avoid breathing dust. For personal protection see section 8.
6.2 Environmental precautions
Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Do NOT let this chemical enter the
environment. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then
store and dispose of according to local regulations.
6.3 Methods and materials for containment and cleaning up
Sweep spilled substance into containers; if appropriate, moisten first to prevent dusting, then remove to safe place. Do NOT let this chemical enter
the environment. Personal protection: P2 filter respirator for harmful particles.
7.Handling and storage
7.1 Precautions for safe handling
Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Avoid exposure - obtain special instructions before use.Provide
appropriate exhaust ventilation at places where dust is formed. For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities
Well closed. Separated from oxidants and food and feedstuffs. Keep in the dark. Ventilation along the floor. Store in an area without drain or
sewer access.Separated from strong oxidants, food and feedstuffs. Keep in the dark. Ventilation along the floor.
8.Exposure controls/personal protection
8.1 Control parameters
Occupational Exposure limit values
Recommended Exposure Limit: 10 Hr Time-Weighted Avg: 5 ppm (20 mg/cu m), skin.
Biological limit values
no data available
8.2 Appropriate engineering controls
Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.
8.3 Individual protection measures, such as personal protective equipment (PPE)
Eye/face protection
Safety glasses with side-shields conforming to EN166. Use equipment for eye protection tested and approved under appropriate government
standards such as NIOSH (US) or EN 166(EU).
Skin protection
Wear impervious clothing. The type of protective equipment must be selected according to the concentration and amount of the dangerous
substance at the specific workplace. Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique(without
touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable
laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive
89/686/EEC and the standard EN 374 derived from it.
Respiratory protection
Wear dust mask when handling large quantities.
Thermal hazards
no data available
9.Physical and chemical properties
Physical state Light grey to light brown flake
Colour Monoclinic tablets, prisms from toluene ... its aqueous solutions soon turn brown
Odour Faint characteristic odor
Melting point/ freezing point 128°C(lit.)
Boiling point or initial boiling point and boiling range 245°C(lit.)
Flammability Combustible SolidCombustible. Gives off irritating or toxic fumes (or gases) in a fire.
Lower and upper explosion limit / flammability limit Flammability lower limit (vapor in air): 1.97%
Flash point 127°C
Auto-ignition temperature 510°C
Decomposition temperature no data available
pH no data available
Kinematic viscosity no data available
Solubility In water:430 g/L (20 oC)
Partition coefficient n-octanol/water (log value) no data available
Vapour pressure 1 mm Hg ( 75 °C)
Density and/or relative density 1.371
Relative vapour density 3.8 (vs air)
Particle characteristics no data available
10.Stability and reactivity
10.1 Reactivity
no data available
10.2 Chemical stability
Discolors in air and light ... its aqueous solution soon turns brown.
10.3 Possibility of hazardous reactions
Combustible when exposed to heat or flame.POISONOUS GASES MAY BE PRODUCED WHEN HEATED. CATECHOL may form toxic
fumes at high temperatures. (USCG, 1999). This compound can react with acid chlorides, acid anhydrides, bases and oxidizing agents. It reacts
violently on contact with concentrated nitric acid. It acts as a reducing agent .
10.4 Conditions to avoid
no data available
10.5 Incompatible materials
Can react vigorously with oxidizing materials
10.6 Hazardous decomposition products
Decomposition compounds: phenol derivatives, carbon oxides, irritating smokes.
11.Toxicological information
Acute toxicity
Oral: LD50 Rat oral 300 mg/kg
Inhalation: no data available
Dermal: no data available
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
Evaluation: No epidemiological data relevant to the carcinogenicity of catechol were available. There is sufficient evidence in experimental animals
for the carcinogenicity of catechol. OVERALL EVALUATION: Catechol is possibly carcinogenic to humans (Group 2B).
Reproductive toxicity
No information is available on the reproductive or developmental effects of catechol in humans or animals.
STOT-single exposure
no data available
STOT-repeated exposure
no data available
Aspiration hazard
no data available
12.Ecological information
12.1 Toxicity
Toxicity to fish: EC50; Species: Pimephales promelas (Fathead minnow); Conditions: flow through bioassay with measured concentrations,
25.6°C, dissolved oxygen 6.4 mg/L, hardness 46.0 mg/L calcium carbonate, alkalinity 40.2 mg/L calcium carbonate, and pH 7.7;
Concentration: 9.00 mg/L for 96 hr (confidence limit: 8.47-9.65 mg/L); Effect: loss of equilibrium
Toxicity to daphnia and other aquatic invertebrates: no data available
Toxicity to algae: EC50; Species: Chlorella vulgaris (Algae); Concentration: >50 mg/L for 10 day; Effect: decreased biomass /Conditions of
bioassay not specified in source examined
Toxicity to microorganisms: no data available
12.2 Persistence and degradability
AEROBIC: Catechol is moderately to readily biodegraded in soils based on a residence time of 1 day for 500 mg of catechol in chernozem soil on
hard carbonaceous woody loam (pH 7.1-7.5, 19°C)(1). The percent biodegradation (measured as percentage of recovered 14CO2 activity) after
6 months at 23°C in Steinbeck loam (pH 5.0), Fallbrook sandy loam (pH 5.5), Greenfield sandy loam (pH 7.0), and Sorrento loam (pH 7.4)
were 24, 50, 28, and 26%, respectively(2). The soil bacteria Agrobacterium radiobacter was shown to biodegrade catechol(3).
12.3 Bioaccumulative potential
An estimated BCF of 3 was calculated for catechol(SRC), using a log Kow of 0.88(1) and a regression-derived equation(2). According to a
classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC).
12.4 Mobility in soil
The Koc of catechol in Brookston clay loam has been reported to be 118(1). According to a classification scheme(2), this Koc value suggests that
catechol is expected to have high mobility in soil.
12.5 Other adverse effects
no data available
13.Disposal considerations
13.1 Disposal methods
Product
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not
contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Contaminated packaging
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it
unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible
packaging materials.
14.Transport information
14.1 UN Number
ADR/RID: UN2811IMDG: UN2811IATA: UN2811
14.2 UN Proper Shipping Name
ADR/RID: TOXIC SOLID, ORGANIC, N.O.S.
IMDG: TOXIC SOLID, ORGANIC, N.O.S.
IATA: TOXIC SOLID, ORGANIC, N.O.S.
14.3 Transport hazard class(es)
ADR/RID: 6.1IMDG: 6.1IATA: 6.1
14.4 Packing group, if applicable
ADR/RID: IIIIMDG: IIIIATA: III
14.5 Environmental hazards
ADR/RID: noIMDG: noIATA: no
14.6 Special precautions for user
no data available
14.7 Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code
no data available
15.Regulatory information
15.1 Safety, health and environmental regulations specific for the product in question
Chemical name Common names and synonyms CAS number EC number
catechol catechol 120-80-9 none
European Inventory of Existing Commercial Chemical Substances (EINECS) Listed.
EC Inventory Listed.
United States Toxic Substances Control Act (TSCA) Inventory Listed.
China Catalog of Hazardous chemicals 2015 Listed.
New Zealand Inventory of Chemicals (NZIoC) Listed.
Philippines Inventory of Chemicals and Chemical Substances (PICCS) Listed.
Vietnam National Chemical Inventory Listed.
Chinese Chemical Inventory of Existing Chemical Substances (China IECSC)Listed.
16.Other information
Information on revision
Creation Date Aug 10, 2017
Revision Date Aug 10, 2017
Abbreviations and acronyms
CAS: Chemical Abstracts Service
ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
IMDG: International Maritime Dangerous Goods
IATA: International Air Transportation Association
TWA: Time Weighted Average
STEL: Short term exposure limit
LC50: Lethal Concentration 50%
LD50: Lethal Dose 50%
EC50: Effective Concentration 50%
References
IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website:
http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
ECHA - European Chemicals Agency, website: https://echa.europa.eu/
Disclaimer: The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this
document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any
guarantee of the properties of the product. We as supplier shall not be held liable for any damage resulting from handling or from contact with the above product.