SAFETY DATA SHEETS
According to Globally Harmonized System of Classification and Labelling of
Chemicals (GHS) - Sixth revised edition
Version: 1.0
Creation Date: Aug 11, 2017
Revision Date: Aug 11, 2017

http://www.phentex.com/Product/Detail-738951.Identification
1.1 GHS Product identifier
Product name L-ascorbic acid
1.2 Other means of identification
Product number -
Other names L-Threoascorbic acid,Antiscorbutic factor,Vitamin C
1.3 Recommended use of the chemical and restrictions on use
Identified uses For industry use only. Processing Aids and Additives
Uses advised against no data available
1.4 Supplier's details
1.5 Emergency phone number
Emergency phone number -
Service hours Monday to Friday, 9am-5pm(Standard time zone: UTC/GMT +8 hours).
2.Hazard identification
2.1 Classification of the substance or mixture
Not classified.
2.2 GHS label elements, including precautionary statements
Pictogram(s) No symbol.
Signal word No signal word.
Hazard statement(s) none
Precautionary statement(s)
Prevention none
Response none
Storage none
Disposal none
2.3 Other hazards which do not result in classification
none
3.Composition/information on ingredients
3.1 Substances
Chemical name Common names and synonyms CAS number EC number Concentration
L-ascorbic acid L-ascorbic acid 50-81-7 none 100%
4.First-aid measures
4.1 Description of necessary first-aid measures
General advice
Consult a physician. Show this safety data sheet to the doctor in attendance.
If inhaled
Fresh air, rest.
In case of skin contact
Remove contaminated clothes. Rinse skin with plenty of water or shower.
In case of eye contact
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
If swallowed
Rinse mouth.
4.2 Most important symptoms/effects, acute and delayed
SYMPTOMS: Symptoms of exposure to this compound may include irritation of the skin, eyes and respiratory tract. Ingestion of large amounts
may cause gastrointestinal distress and diarrhea. Exposure may also cause the formation of renal calciumoxalate calculi. There have been cases of
allergic reaction with eczema, urticaria and asthma. The mucolytic effect of this compound might render the cervical mucus less permeable to
spermatozoa. ACUTE/CHRONIC HAZARDS: This compound may cause irritation of the skin, eyes and respiratory tract. When heated to
decomposition it emits acrid smoke and irritating fumes.
4.3 Indication of immediate medical attention and special treatment needed, if necessary
All sources of vitamin C should be withdrawn and treatment for gastrointestinal symptoms provided, including antiemetics. If significant hemolysis
occurs, intravenous hydration to maintain urine output should be administered. Monitoring renal function should be performed, and rarely,
transfusion of packed red blood cells is required.
5.Fire-fighting measures
5.1 Extinguishing media
Suitable extinguishing media
Fires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher. A water spray may also be used.
5.2 Specific hazards arising from the chemical
Flash point data for this chemical are not available; however, it is probably combustible.
5.3 Special protective actions for fire-fighters
Wear self-contained breathing apparatus for firefighting if necessary.
6.Accidental release measures
6.1 Personal precautions, protective equipment and emergency procedures
Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel
to safe areas. Avoid breathing dust. For personal protection see section 8.
6.2 Environmental precautions
Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Sweep spilled substance into covered
containers. If appropriate, moisten first to prevent dusting. Wash away remainder with plenty of water.
6.3 Methods and materials for containment and cleaning up
Pick up and arrange disposal. Sweep up and shovel. Keep in suitable, closed containers for disposal.
7.Handling and storage
7.1 Precautions for safe handling
Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Avoid exposure - obtain special instructions before use.Provide
appropriate exhaust ventilation at places where dust is formed. For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities
Separated fromstrong oxidants and strong bases.Solutions of ascorbic acid are rapidly oxidized in air and in alkaline media; the drug should be
protected fromair and light.
8.Exposure controls/personal protection
8.1 Control parameters
Occupational Exposure limit values
no data available
Biological limit values
no data available
8.2 Appropriate engineering controls
Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.
8.3 Individual protection measures, such as personal protective equipment (PPE)
Eye/face protection
Safety glasses with side-shields conforming to EN166. Use equipment for eye protection tested and approved under appropriate government
standards such as NIOSH (US) or EN 166(EU).
Skin protection
Wear impervious clothing. The type of protective equipment must be selected according to the concentration and amount of the dangerous
substance at the specific workplace. Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique(without
touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable
laws
and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive
89/686/EEC and the standard EN 374 derived fromit.
Respiratory protection
Wear dust mask when handling large quantities.
Thermal hazards
no data available
9.Physical and chemical properties
Physical state White to very pale yellow crystalline powder with a pleasant sharp acidic taste
Colour Crystals (usually plates, sometimes needles, monoclinic system)
Odour Odorless
Melting point/ freezing point 192°C(lit.)
Boiling point or initial boiling point and boiling range 83°C/44mmHg(lit.)
Flammability Combustible.
Lower and upper explosion limit / flammability limit no data available
Flash point 15°C(lit.)
Auto-ignition temperature 660°C
Decomposition temperature 190-192°C
pH Between 2,4 and 2,8 (2?% aqueous solution)
Kinematic viscosity no data available
Solubility In water:333 g/L (20 oC)
Partition coefficient n-octanol/water (log value) no data available
Vapour pressure 9.28X10-11 mmHg at 25°C (est)
Density and/or relative density 1.7
Relative vapour density no data available
Particle characteristics no data available
10.Stability and reactivity
10.1 Reactivity
no data available
10.2 Chemical stability
Stable to air when dry; impure preparation and in many natural products vitamin oxidizes on exposure to air and light. Aqueous solutions are
rapidly oxidized by air, accelerated by alkalies, iron, copper
10.3 Possibility of hazardous reactions
L-ASCORBIC ACID is a lactone. Reacts as a relatively strong reducing agent and decolorizes many dyes. Forms stable metal salts. Incompatible
with oxidizers, dyes, alkalis, iron and copper. Also incompatible with ferric salts and salts of heavy metals, particularly copper, zinc and manganese
. 1
0.4 Conditions to avoid
no data available
10.5 Incompatible materials
no data available
10.6 Hazardous decomposition products
When heated to decomposition it emits acrid smoke and irritating fumes.
11.Toxicological information
Acute toxicity
Oral: LD50 Rat oral 11,900 mg/kg
Inhalation: no data available
Dermal: no data available
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germcell mutagenicity
no data available
Carcinogenicity
no data available
Reproductive toxicity
no data available
STOT-single exposure
no data available
STOT-repeated exposure
no data available
Aspiration hazard
no data available
12.Ecological information
12.1 Toxicity
Toxicity to fish: LC50 Species: /Oncorhynchus mykiss/ (Rainbow trout); Concentration: 1,020 mg/L for 96 hr /Conditions of bioassay not
specified in source examined
Toxicity to daphnia and other aquatic invertebrates: no data available
Toxicity to algae: no data available
Toxicity to microorganisms: no data available
12.2 Persistence and degradability
AEROBIC: Using a mixed microbial consortia enriched fromuntreated sewage samples collected in the vicinity of a primary treatment plant in
Delhi, India, L-ascorbic acid exhibited 36.7 mg/L BOD, suggesting moderate susceptibility to biodegradation(1).
12.3 Bioaccumulative potential
An estimated BCF of 3 was calculated in fish for L-ascorbic acid(SRC), using a log Kow of -1.85(1) and a regression-derived equation(2).
According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC).
12.4 Mobility in soil
The Koc of L-ascorbic acid is estimated as 10(SRC), using a log Kow of -1.85(1) and a regression-derived equation(2). According to a
classification scheme(3), this estimated Koc value suggests that L-ascorbic acid is expected to have very high mobility in soil. The pKa of Lascorbic acid is 4.70(4), indicating that this compound will exist almost entirely in the anion formin the environment and anions generally do not
adsorb more strongly to soils containing organic carbon and clay than their neutral counterparts(5).
12.5 Other adverse effects
no data available
13.Disposal considerations
13.1 Disposal methods
Product
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not
contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Contaminated packaging
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it
unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible
packaging materials.
14.Transport information
14.1 UN Number
ADR/RID: Not dangerous goods. IMDG: Not dangerous goods. IATA: Not dangerous goods.
14.2 UN Proper Shipping Name
ADR/RID: unknown
IMDG: unknown
IATA: unknown
14.3 Transport hazard class(es)
ADR/RID: Not dangerous goods. IMDG: Not dangerous goods. IATA: Not dangerous goods.
14.4 Packing group, if applicable
ADR/RID: Not dangerous goods. IMDG: Not dangerous goods. IATA: Not dangerous goods.
14.5 Environmental hazards
ADR/RID: no IMDG: no IATA: no
14.6 Special precautions for user
no data available
14.7 Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code
no data available
15.Regulatory information
15.1 Safety, health and environmental regulations specific for the product in question
Chemical name Common names and synonyms CAS number EC number
L-ascorbic acid L-ascorbic acid 50-81-7 none
European Inventory of Existing Commercial Chemical Substances (EINECS) Listed.
EC Inventory Listed.
United States Toxic Substances Control Act (TSCA) Inventory Listed.
China Catalog of Hazardous chemicals 2015 Not Listed.
NewZealand Inventory of Chemicals (NZIoC) Listed.
Philippines Inventory of Chemicals and Chemical Substances (PICCS) Listed.
VietnamNational Chemical Inventory Listed.
Chinese Chemical Inventory of Existing Chemical Substances (China IECSC) Listed.
16.Other information
Information on revision
Creation Date Aug 11, 2017
Revision Date Aug 11, 2017
Abbreviations and acronyms
CAS: Chemical Abstracts Service
ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
IMDG: International Maritime Dangerous Goods
IATA: International Air Transportation Association
TWA: Time Weighted Average
STEL: Short termexposure limit
LC50: Lethal Concentration 50%
LD50: Lethal Dose 50%
EC50: Effective Concentration 50%
References
IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website:
http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
ECHA - European Chemicals Agency, website: https://echa.europa.eu/
Disclaimer: The above information is believedto be correct but does not purport to be all inclusive andshall be usedonly as a guide. The information in this
document is basedon the present state of our knowledge andis applicable to the product with regardto appropriate safety precautions. It does not represent any
guarantee of the properties of the product. We as supplier shall not be heldliable for any damage resulting from handling or from contact with t

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