SAFETY DATA SHEETS
According to Globally Harmonized System of Classification and Labelling of
Chemicals (GHS) - Sixth revised edition
Version: 1.0
Creation Date: Aug 12, 2017
Revision Date: Aug 12, 2017
1.Identification
1.1 GHS Product identifier
Product name 1-ethoxy-2-(2-ethoxyethoxy)ethane
1.2 Other means of identification
Product number-
Other names Ethane, 1,1‘-oxybis[2-ethoxy-
1.3 Recommended use of the chemical and restrictions on use
Identified uses For industry use only. Processing aids, not otherwise listed
Uses advised againstno data available
1.4 Supplier's details
1.5 Emergency phone number
Emergency phone number-
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).
2.Hazard identification
2.1 Classification of the substance or mixture
Skin irritation, Category 2
2.2 GHS label elements, including precautionary statements
Pictogram(s)
Signal word Warning
Hazard statement(s) H315 Causes skin irritation
Precautionary statement(s)
Prevention
P264 Wash ... thoroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
Response
P302+P352 IF ON SKIN: Wash with plenty of water/...
P321 Specific treatment (see ... on this label).
P332+P313 If skin irritation occurs: Get medical advice/attention.
P362+P364 Take off contaminated clothing and wash it before reuse.
none
Storage
none
Disposal none
2.3 Other hazards which do not result in classification
none
3.Composition/information on ingredients
3.1 Substances
Chemical name Common names and synonyms CAS numberEC numberConcentration
1-ethoxy-2-(2-ethoxyethoxy)ethane1-ethoxy-2-(2-ethoxyethoxy)ethane112-36-7 none 100%
4.First-aid measures
4.1 Description of necessary first-aid measures
General advice
Consult a physician. Show this safety data sheet to the doctor in attendance.
If inhaled
Fresh air, rest.
In case of skin contact
Remove contaminated clothes. Rinse skin with plenty of water or shower.
In case of eye contact
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
If swallowed
Rinse mouth.
4.2 Most important symptoms/effects, acute and delayed
SYMPTOMS: Symptoms of exposure to this compound include irritation of the skin, eyes, mucous membranes and respiratory tract, coughing,
dyspnea and kidney damage. Other symptoms may include nausea, vomiting, headache and central nervous system depression. Exposure may also
cause diarrhea, abdominal and lumbar pain, mild liver damage, pulmonary edema, transient polyuria, oliguria, anuria and death by acute renal
failure. ACUTE/CHRONIC HAZARDS: This compound may be harmful by inhalation, ingestion or skin absorption. It is an irritant of the skin,
eyes, mucous membranes and respiratory tract. When heated to decomposition it emits acrid smoke, irritating fumes and toxic fumes of carbon
monoxide and carbon dioxide.
4.3 Indication of immediate medical attention and special treatment needed, if necessary
Basic treatment: Establish a patent airway (oropharyngeal or nasopharyngeal airway, if needed). Suction if necessary. Watch for signs of
respiratory insufficiency and assist ventilations if necessary. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for pulmonary
edema and treat if necessary ... . Monitor for shock and treat if necessary ... . Anticipate seizures and treat if necessary ... . For eye contamination,
flush eyes immediately with water. Irrigate each eye continuously with 0.9% saline (NS) during transport ... . Do not use emetics. For ingestion,
rinse mouth and administer 5 ml/kg up to 200 ml of water for dilution if the patient can swallow, has a strong gag reflex, and does not drool.
Administer activated charcoal ... . /Ethylene glycol, glycols, and related compounds/
5.Fire-fighting measures
5.1 Extinguishing media
Suitable extinguishing media
Fires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher.
5.2 Specific hazards arising from the chemical
This chemical is combustible.
5.3 Special protective actions for fire-fighters
Wear self-contained breathing apparatus for firefighting if necessary.
6.Accidental release measures
6.1 Personal precautions, protective equipment and emergency procedures
Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel
to safe areas. Avoid breathing dust. For personal protection see section 8.
6.2 Environmental precautions
Collect leaking liquid in sealable containers. Wash away remainder with plenty of water.
6.3 Methods and materials for containment and cleaning up
Pick up and arrange disposal. Sweep up and shovel. Keep in suitable, closed containers for disposal.
7.Handling and storage
7.1 Precautions for safe handling
Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Avoid exposure - obtain special instructions before use.Provide
appropriate exhaust ventilation at places where dust is formed. For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities
Separated from strong oxidants. Ventilation along the floor.
8.Exposure controls/personal protection
8.1 Control parameters
Occupational Exposure limit values
no data available
Biological limit values
no data available
8.2 Appropriate engineering controls
Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.
8.3 Individual protection measures, such as personal protective equipment (PPE)
Eye/face protection
Safety glasses with side-shields conforming to EN166. Use equipment for eye protection tested and approved under appropriate government
standards such as NIOSH (US) or EN 166(EU).
Skin protection
Wear impervious clothing. The type of protective equipment must be selected according to the concentration and amount of the dangerous
substance at the specific workplace. Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique(without
touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable
laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive
89/686/EEC and the standard EN 374 derived from it.
Respiratory protection
Wear dust mask when handling large quantities.
Thermal hazards
no data available
9.Physical and chemical properties
Physical state colourless liquid
Colour Colorless liquid
Odour no data available
Melting point/ freezing point -44.3oC
Boiling point or initial boiling point and boiling range 180-190°C(lit.)
Flammability Combustible.
Lower and upper explosion limit / flammability limit no data available
Flash point 67°C
Auto-ignition temperature 205°C
Decomposition temperature no data available
pH no data available
Kinematic viscosity no data available
Solubility In water:SOLUBLE
Partition coefficient n-octanol/water (log value) log Kow = 0.39
Vapour pressure 0.5 mm Hg ( 20 °C)
Density and/or relative density 0.909g/mLat 25°C(lit.)
Relative vapour density 5.6 (vs air)
Particle characteristics no data available
10.Stability and reactivity
10.1 Reactivity
no data available
10.2 Chemical stability
Extremely stable
10.3 Possibility of hazardous reactions
CombustibleDIETHYLENE GLYCOL DIETHYL ETHER is incompatible with strong acids. It is also incompatible with strong oxidizing agents.
10.4 Conditions to avoid
no data available
10.5 Incompatible materials
Glycol ethers, glycols, ketones, and alcohols undergo violent decomposition in contact with 68-72% perchloric acid
10.6 Hazardous decomposition products
When heated to decomposition it emits acrid smoke and irritating fumes.
11.Toxicological information
Acute toxicity
Oral: LD50 Rat oral 4970 mg/kg
Inhalation: no data available
Dermal: no data available
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
no data available
Reproductive toxicity
no data available
STOT-single exposure
no data available
STOT-repeated exposure
no data available
Aspiration hazard
no data available
12.Ecological information
12.1 Toxicity
Toxicity to fish: no data available
Toxicity to daphnia and other aquatic invertebrates: no data available
Toxicity to algae: no data available
Toxicity to microorganisms: no data available
12.2 Persistence and degradability
AEROBIC: An aerobic biodegradation study using gram-negative asporogenous rod bacterium isolated from soil by enrichment on triethylene
glycol exhibited borderline growth (scarcely detectable growth, not reproducible) with diethylene glycol diethyl ether(1). In a screening study using
a sewage seed, diethylene glycol diethyl ether (concentration not specified) had a 10 day BOD of 0.10 g/g (4.2% theoretical BOD) at 20°C(2).
Diethylene glycol diethyl ether had a 21.7% COD removal at 30°C from a starting concentration of 600 mg COD/L (time period not given)
indicating little degradation compared to 95% degradation of ethylene glycol monophenyl ether(3).
12.3 Bioaccumulative potential
An estimated BCF of 3 was calculated in fish for diethylene glycol diethyl ether(SRC), using a log Kow of 0.39(1) and a regression-derived
equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC).
12.4 Mobility in soil
The Koc of diethylene glycol diethyl ether is estimated as 39(SRC), using a log Kow of 0.39(1) and a regression-derived equation(2). According
to a classification scheme(3), this estimated Koc value suggests that diethylene glycol diethyl ether is expected to have very high mobility in soil.
12.5 Other adverse effects
no data available
13.Disposal considerations
13.1 Disposal methods
Product
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not
contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Contaminated packaging
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it
unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible
packaging materials.
14.Transport information
14.1 UN Number
ADR/RID: no data availableIMDG: no data availableIATA: no data available
14.2 UN Proper Shipping Name
ADR/RID: no data available
IMDG: no data available
IATA: no data available
14.3 Transport hazard class(es)
ADR/RID: no data availableIMDG: no data availableIATA: no data available
14.4 Packing group, if applicable
ADR/RID: no data availableIMDG: no data availableIATA: no data available
14.5 Environmental hazards
ADR/RID: noIMDG: noIATA: no
14.6 Special precautions for user
no data available
14.7 Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code
no data available
15.Regulatory information
15.1 Safety, health and environmental regulations specific for the product in question
Chemical name Common names and synonyms CAS numberEC number
1-ethoxy-2-(2-ethoxyethoxy)ethane1-ethoxy-2-(2-ethoxyethoxy)ethane112-36-7 none
European Inventory of Existing Commercial Chemical Substances (EINECS) Listed.
EC Inventory Listed.
United States Toxic Substances Control Act (TSCA) Inventory Listed.
China Catalog of Hazardous chemicals 2015 Not Listed.
New Zealand Inventory of Chemicals (NZIoC) Listed.
Philippines Inventory of Chemicals and Chemical Substances (PICCS) Listed.
Vietnam National Chemical Inventory Listed.
Chinese Chemical Inventory of Existing Chemical Substances (China IECSC) Listed.
16.Other information
Information on revision
Creation Date Aug 12, 2017
Revision Date Aug 12, 2017
Abbreviations and acronyms
CAS: Chemical Abstracts Service
ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
IMDG: International Maritime Dangerous Goods
IATA: International Air Transportation Association
TWA: Time Weighted Average
STEL: Short term exposure limit
LC50: Lethal Concentration 50%
LD50: Lethal Dose 50%
EC50: Effective Concentration 50%
References
IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website:
http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
ECHA - European Chemicals Agency, website: https://echa.europa.eu/
Disclaimer: The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this
document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any
guarantee of the properties of the product. We as supplier shall not be held liable for any damage resulting from handling or from contact with the above product.